Latest research at the Laboratory of Genetics

Our research explores in vitro cross-kingdom interactions in Lithuanian farmlands.

The aim of the study was to investigate the occurrence of antibiotic-resistant bacteria and yeasts in interconnected pasture-associated environments (soil, feed, and freshwater) and to assess their potential interactions.

Bacterial isolates were characterised under antibiotic-selective conditions and by minimum inhibitory concentration assay, while yeast isolates were evaluated for antagonistic activity against sensitive yeasts and antibiotic-resistant bacterial strains.

We have found a frequent occurrence of multidrug-resistant bacteria, and several antagonistic yeast exhibiting activity against both kingdoms.

Our findings reveal a phenotypic exploration of potential cross-kingdom interactions within agricultural niches, suggesting the influence of the antagonistic activity on proliferation and persistence of antibiotic-resistant bacteria.

More about the research: https://www.mdpi.com/2076-2607/14/5/991

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