The Laboratory of Genetics performs fundamental and applied research on the structure and functioning of natural and model microbiosystems. Using metagenomic methods, the diversity of prokaryotic and eukaryotic microorganisms as well as yeast viruses distributed in natural ecosystems is evaluated, and searching for microorganisms with biocontrol properties and their functionality studies are carried out. Using high-throughput next generation sequencing and bioinformatics analysis, the communities of microorganisms on natural and technological objects are determined. The effect of individual components of microbiota on the structure and functionality of microbial communities is examined. Microbiological contamination of water, feed, raw food materials and products is assessed using the methods of microorganism cultivation and molecular analysis. The spread of microorganisms potentially harmful to the environment and humans is analyzed. Screening and evaluation of antimicrobial and antiviral factors are carried out, and the effectiveness of biocidal systems and materials is modulated to elucidate their mechanisms of action and expand the prospects of application in the food industry, health care and agriculture. By applying functional genomics, transcriptomic and proteomic techniques, the cellular stress response and resistance formation mechanisms are studied. Systematic knowledge of the structure, molecular mechanisms of the assembly and functioning of microbiosystems contributes to the sustainable use and preservation of bioecosystems.
